Personalized medicine in adult acute lymphoblastic leukemia.

Artistic illustration of aspects of 'innovation in hematology'-the new theme of the year of the European Hematology Association. Editorials 849 The search for the origin of factor VIII synthesis and its impact on therapeutic strategies for hemophilia A 853 Rituximab maintenance therapy in diffuse large B-cell lymphoma: is XY the most important variable? Review Article 859 Reduced intensity conditioning allogeneic hematopoietic cell transplantation for adult acute myeloid leukemia in complete remission-a review from the Acute Leukemia Working Party of the EBMT Salyka Sengsayadeth, et al. 870 Dietary ω-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease Brian T. Kalish, et al. 893 Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations Carla Al Assaf, et al. 898 A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generation c-ABL therapy Gautam Borthakur, et al.